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rifampin will lessen the level or impact of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use warning/Monitor. For sufferers receiving exemestane having a potent CYP3A4 inducer the encouraged dose of exemestane is 50 mg day-to-day after a meal. dexamethasone will lower the level or impact of exemestane by affecting hepatic/i